What are the side effects of aloe?

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The side effects of aloe depend on which part you use and how you use it. Putting aloe gel on your skin is safe for most people. Drinking aloe latex by mouth is a whole different story. The FDA and IARC have both raised red flags about oral latex. You need to know the difference between gel and latex before using any aloe product.

When I first grew aloe at home, I figured every part of the plant was equally safe. I'd heard people drank aloe juice so I didn't think twice about it. Then I looked into the aloe vera risks tied to the yellow sap under the leaf skin. That reading changed my mind fast. The clear inner gel is your safe zone. The yellow stuff between the gel and the green skin is what causes problems when you swallow it.

The bad actor in aloe latex is a compound called aloin. It works as a harsh laxative that can give you cramps, diarrhea, and fluid loss. The cancer risk is the scarier part though. NTP studies found that rats given 60 ppm of aloin daily grew tumors in their guts. That finding pushed health agencies to crack down on oral aloe latex products sold to the public.

The aloe latex dangers led to real action from the government. In 2002 the FDA banned aloe latex in over-the-counter laxatives. IARC labeled whole leaf aloe extract as a possible cancer risk for humans. The NIEHS set a safety cap of 10 ppm aloin for products you drink. All of these steps tell you that oral aloe latex is not something to mess with on your own.

Aloe Product Safety Levels
Aloe ProductTopical gel (skin)Risk Level
Low risk
Key ConcernRare contact dermatitis
Aloe ProductDecolorized juiceRisk Level
Moderate risk
Key ConcernLimited safety data
Aloe ProductWhole leaf extractRisk Level
Higher risk
Key ConcernIARC possible carcinogen
Aloe ProductOral aloe latexRisk Level
Highest risk
Key ConcernFDA banned in laxatives
Risk levels based on current FDA, IARC, and NCCIH guidance as of 2024.

You should know about several aloe vera safety concerns for certain groups. If you're pregnant or nursing, skip oral aloe since aloin may start contractions. It can also pass through breast milk to your baby. If you take diabetes drugs, oral aloe may drop your blood sugar too low. Anyone on blood thinners should also talk to their doctor before drinking aloe products of any kind.

The tricky part about shopping for aloe drinks is that no law makes companies list aloin levels on their labels. You can't always tell from the bottle how much latex ended up in the final product. When I buy aloe drinks now, I only grab ones that say decolorized on the label. That process strips out most of the harmful aloin and makes the product much safer for you to consume. I also started checking with my doctor before trying any new oral aloe product just to be safe.

My bottom line advice is this. Put aloe gel on your skin all you want since the safety record is strong and the side effects of aloe gel are minimal. If you want to take any aloe product by mouth, talk to your doctor first. Choose decolorized options and keep your doses small. Use the fresh gel from your home plant for burns and skin care, but keep that yellow latex layer out of your body. When I harvest gel from my aloe now, I always rinse the leaf first and let the yellow sap drip out for a few minutes before scooping the clear gel. That simple step keeps the latex away from my skin and out of whatever I'm using the gel for. A little bit of care goes a long way with this plant.

Read the full article: Aloe Plant Care and Growing Guide

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