What makes neem oil effective against fungal conditions?

Written by
Michael Sullivan
Reviewed by
Prof. Samuel Fitzgerald, Ph.D.The effectiveness of neem oil against fungi is derived from its special biochemical composition. The sulfur compounds present penetrate the cell walls of the fungi, thereby disturbing functions essential to the maintenance of the fungi. The compounds nimbin and nimbidin specifically inhibit the germination of spores. This double function makes it particularly effective against certain obstinate strains of fungi. It can be used safely when properly diluted for all conditions.
The antimicrobial properties confer protection against a broad spectrum of fungi. The agents contained therein penetrate the protective membranes surrounding the cells, causing effusion of the interior contents, with consequent death of the organism. The anti-inflammatory properties at the same time reduce the redness and swelling in the irritated membranes, thus attacking both the cause and the symptoms with success.
Biochemical Action
- Sulfur disruption: Blocks ergosterol synthesis in cell membranes
- Spore inhibition: Prevents germination and spread
- Enzyme interference: Disables fungal metabolic pathways
Therapeutic Applications
- Plant mildew: 0.5% spray every 5-7 days
- Athlete's foot: 1% solution twice daily
- Ringworm: Apply with coconut oil base
Enhanced Formulations
- Tea tree synergy: Boosts antifungal potency
- Carrier oils: Improve skin penetration
- Emulsifiers: Ensure even distribution on leaves
Certain plant treatment regimens need scheduling. Spray in the early morning when the air is cooler, as leaf absorption is most effective at this time of day. Spray leaves completely, top and bottom. Retreatments keep up protective barriers when humidity prevails. Always test a few leaves before treating the entire plant. This way, phytotoxicity will not be caused in sensitive species.
Human skin treatment must be carefully diluted, not exceeding 2% concentration if there is going to be any application to the skin. They should be mixed with a carrier oil, such as jojoba, for the best results. Do not use if irritation occurs. Fungi that do not improve within 2 weeks require medical attention. Natural cures supplement but do not supplant professional attention.
Read the full article: 10 Essential Neem Oil Uses You Should Know